(calcipotriene and betamethasone dipropionate)
Cream, 0.005%/0.064%


Wynzora®️ Cream is a novel topical treatment for plaque psoriasis which offers a unique combination of high efficacy, favorable safety and excellent treatment convenience in a single product.

Important Safety Information

What is Wynzora® Cream?
Wynzora® (calcipotriene and betamethasone dipropionate) Cream is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults. It is not known if Wynzora® Cream is safe and effective in children.

Wynzora® Cream is for use on skin only (topical). Do not get Wynzora® Cream near or in your mouth, eyes, or vagina. Avoid using Wynzora® Cream on your face, groin, or armpits, or if you have thinning of your skin (atrophy) at the treatment site.

How should I use Wynzora® Cream?
Apply Wynzora® Cream to the affected areas of your skin once a day for up to 8 weeks. You should stop treatment when your plaque psoriasis is under control unless your healthcare provider gives you other instructions.

Do not use more than 100 grams of Wynzora® Cream per week.

What should I tell with my healthcare provider before starting Wynzora® Cream?
Tell your healthcare provider about all your medical conditions and all the medicines you take, including any corticosteroid medicines and any other products containing calcipotriene.

Do not use other products containing calcipotriene or a corticosteroid medicine without talking to your healthcare provider first.

What are the possible side effects of Wynzora® Cream?
Wynzora® Cream may cause side effects including:

  • Too much calcium in your blood or urine and/or adrenal gland problems
  • Cushing’s syndrome, a condition that happens when your body is exposed to large amounts of the hormone cortisol.
  • High blood sugar and sugar in your urine
  • Vision problems, including an increased risk of developing cataracts and glaucoma.

The most common side effects include upper respiratory infection, headache, and application site irritation. These are not all the possible side effects. Call your healthcare provider for medical advice about side effects.

You are encouraged to report side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

You may also report side effects to MC2 Therapeutics Inc. at 1-800-644-8240.

Where do I learn more?
This summary is not comprehensive. To learn more, talk to your healthcare provider or pharmacist about Wynzora® Cream. Further, read the information that comes with your prescription.

Visit to obtain the FDA-approved Full Prescribing Information.

© mc2 therapeutics 2020